Stable CAD does not SIGNIFY ivabradine therapy

Does Ivabradine SIGNIFY Improvements in Quality of Life?

Bradycardia and atrial fibrillation in patients with stable coronary artery disease treated with ivabradine: an analysis from the SIGNIFY study.

AIM The aim of this study was to determine the impact of emergent bradycardia and atrial fibrillation (AF) on cardiovascular outcomes in 19 083 patients with stable coronary artery disease (CAD) receiving ivabradine or placebo (SIGNIFY, Study assessInG the morbidity-mortality beNefits of the If inhibitor ivabradine in patients with coronarY artery disease). METHODS AND RESULTS Emergent bradyc...

What does left - right autonomic asymmetry signify ?

(2015) What does left-right autonomic asymmetry signify? This document is made available in accordance with publisher policies and may differ from the published version or from the version of record. If you wish to cite this item you are advised to consult the publisher's version. Please see the URL above for details on accessing the published version. Copyright and all moral rights to the vers...

Percutaneous coronary intervention plus optimal medical therapy was not more effective than medical therapy alone in stable CAD.

M e t h o d s Design: Randomized controlled trial (Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation [COURAGE] trial). Allocation: Unclear allocation concealment.* Blinding: Blinded (outcome adjudication committee).* Follow-up period: Median 4.6 years (range 2.5 to 7.0 y). Setting: 50 centers in the United States and Canada. Patients: 2287 patients (mean age 62 y, 85%...

Cancellation Does Not Imply Stable Rank One

An unital C∗-algebra A is said to have cancellation of projections if the semigroup D(A) of Murray-von Neumann equivalence classes of projections in matrices over A is cancellative. It has long been known that stable rank one implies cancellation for any A, and some partial converses have been established. In the sequel it is proved that cancellation does not imply stable rank one for simple, s...